Phytochemical profiling of the different organs of Cupressus sempervirens L. by LC-HR/MS

Cupressus sempervirens L. which is largely used in traditional medicine was collected from the Florya Atatürk Forest (İstanbul, Türkiye) to investigate phytochemical profiling and antioxidant capacity of seeds cones. The activities hexane methanol extracts C. were assessed vitro using five complementary methods, including β-carotene-linoleic acid assay for lipid peroxidation activity, DPPH•, ABTS• assays radical-scavenging CUPRAC method, metal chelating methods. In addition, phenolic cones analyzed LC-HR/MS, first time. According findings, activity extract obtained appears be higher than that all assays. showed with an IC50: 24.081.06, 6.080.19, A0.5: 18.600.63 µg/mL ABTS•, assays, respectively BHA, α-TOC. Also, strong 38.870.03 A0.5:103.534.33 scavenging Moreover, twenty-eight phenolics determined while twenty-one LC-HR/MS. amounts fumaric acid, vanilic (-)-epicatechin, quercetin, hispidulin 7-glucoside, hyperoside, quercitrin are those Therefore, results suggested there a relationship between their ingredients.